Description

5-formyl-dC is mutagenic and has been shown to induce the 5-fC →T transition mutation as well as 5-fC →A and 5-fC →G transversion mutations during DNA synthesis, particularly in methylated CpG regions (Kamiya et al., Münzel et al.)

Product Details

Catalog NoN-2064

Purity≥90% by AX-HPLC

Extinction Coefficient11,000 Lmol-1cm-1 at 283 nm

Molecular FormulaC10H16N3O14P3 (free acid)

Molecular Weight495.10 g/mole (free acid)

Salt FormLi+

Concentration100 mM

BufferH2O

Recommended Storage-20°C or below

Other Name(s)5-Formyl-dCTP, 5-fdCTP,5-CHO-dCTP, 5-Fo-dCTP

ApplicationAptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies

Backbone5'-Triphosphate

Base Analog(s)Cytidine

Sugar Type(s)DNA

Nucleotide CategoryBase Modified DNA